失神癫痫如何治疗配图,仅供参考
Nonmotor (absence) seizureFirst single drug
Ethosuximide or valproate is recommended for absence seizures. Lamotrigine can be considered if ethosuximide or valproate is inappropriate,ineffective,or not tolerated by the patient. A large study of ethosuximide,valproate,and lamotrigine demonstrated the superior effectiveness of ethosuximide and valproate compared with lamotrigine as a first-line treatment for patients with absence seizure. A 2010 double-blind trial of 446 patients with absence seizure found that the rate of seizure-free outcomes was 58% for valproate,53% for ethosuximide,and 29% for lamotrigine. If the patient has coexisting generalized tonic-clonic seizures,valproate should be considered in preference to ethosuximde.
Additional drug
If the primary treatment is not effective or is not tolerated by the patient,two of the following drugs can be considered: ethosuximide,lamotrigine,and valproate. If the additional treatment is ineffective or the patient cannot tolerate it,the patient can be transferred to a tertiary institution. Clobazam,clonazepam,levetiracetam,topiramate,and zonisamide can be considered as a next step.","department":"
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